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侯凡凡院士集
  • 侯凡凡主编 著
  • 出版社: 北京:人民军医出版社
  • ISBN:9787509177624
  • 出版时间:2014
  • 标注页数:571页
  • 文件大小:264MB
  • 文件页数:589页
  • 主题词:侯凡凡-生平事迹

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图书目录

第一部分 奋斗历程1

侯凡凡院士简历3

第二部分 学术贡献7

一、侯凡凡院士的学术成就与学术思想9

二、侯凡凡院士的主要学术论文13

(一)临床研究论文13

Efficacy and Safety of Benazepril for Advanced Chronic Renal Insufficiency13

Renoprotection of Optimal Antiproteinuric Doses (ROAD) Study:A Randomized Controlled Study of Benazepril and Losartan in Chronic Renal Insufficiency23

Urinary Angiotensinogen Level Predicts Acute Kidney Injury in Acute Decompensated Heart Failure:a Prospective,Two-Stage Study34

Enhanced Expression of Receptor for Advanced Glycation End Products in Chronic Kidney Disease49

Receptor for Advanced Glycation End Products on Human Synovial Fibroblasts:Role in the Pathogenesis of Dialysis-Related Amyloidosis58

Accumulation of Tissue Advanced Glycation End Products Correlated with Glucose Exposure Dose and Associated with Cardiovascular Morbidity in Patients on Peritoneal Dialysis70

Renal Expression of Advanced Oxidative Protein Products Predicts Progression of Renal Fibrosis in Patients with IgA Nephropathy80

Metabolic Syndrome, but Not Insulin Resistance, is Associated with an Increased Risk of Renal Function Decline93

High Level of Proteinuria During Treatment With Renin—Angiotensin Inhibitors Is A Strong Predictor of Renal Outcome in Nondiabetic Kidney Disease102

Successful Treatment of Massive Ascites with Intraperitoneal Administration of a Steroid in a Case of Systemic Lupus Erythematosus112

Increased Plasma Advanced Oxidation Protein Products is an Early Marker of Endothelial Dysfunction in Type 2 Diabetes Patients Without Albuminuria115

(二)基础研究论文124

Kindlin-2 Mediates Activation of TGF-β/Smad Signaling and Renal Fibrosis124

A Salt-Induced Reno-Cerebral Reflex Activates RAS and Promotes CKD Progression139

GQ5 Hinders Renal Fibrosis in Obstructive Nephropathy by Selectively Inhibiting TGF-β-Induced Smad3 Phosphorylation166

Advanced Oxidation Protein Products Accelerate Renal Fibrosis in A Remnant Kidney Model184

Aminoguanidine Inhibits Advanced Glycation End Products Formation on β2-Microglobulin195

The Receptor of Advanced Glycation End Products Plays A Central Role In Advanced Oxidation Protein Products Induced Podocyte Apoptosis202

Accumulation of Advanced Oxidation Protein Products Induces Podocyte Apoptosis and Deletion Through NADPH-Dependent Mechanisms215

Restricted Intake of Dietary Advanced Glycation End Products Retards Renal Progression in the Remnant Kidney Model231

β2-Microglobulin Modified with Advanced Glycation End Products Delays Monocyte Apoptosis244

β2-Microglobulin Modified with Advanced Glycation End Products Modulates Collagen Synthesis by Human Fibroblasts258

Interaction Between β2-Microglobulin and Advanced Glycation End Products in the Development of Dialysis Related- Amyloidosis268

Advanced Oxidation Protein Products Activate Intrarenal Renin-Angiotensm System Via a CD36-Mediated, Redox-Dependent Pathway275

Advanced Oxidation Protein Products Activate Vascular Endothelial Cells via a RAGE-Mediated Signaling Pathway294

Picrorhiza Scrophulariiflora Improves Accelerated Atherosclerosis Through Inhibition of Redox-Sensitive Inflammation309

Lingzhiols,Unprecedented Rotary Door Shaped Meroterpenoids as Potent and Selective Inhibitors of p-Smad3 from Ganoderma lucidum319

Acortatarins A and B, Two Novel Antioxidative Spiroalkaloids with A Naturally Unusual Morpholine Motif from Acorus Tatarinowii324

Advanced Oxidation Protein Products Accelerate Atherosclerosis Through Promoting Oxidative Stress and Inflammation329

AGE-LDL Activates Toll Like Receptor 4 Pathway and Promotes Inflammatory Cytokines Production in Renal Tubular Epithelial Cells337

Salt-Induced Changes in Cardiac Phosphoproteome in a Rat Model of Chronic Renal Failure350

Albumin Overload Activates Intrarenal Renin-Angiotensin System Through Protein Kinase C and NADPH Oxidasedependent Pathway362

Bioactive Compounds from the Aerial Parts of Brachystemma Calycinum and Structural Revision of An Octacyclopeptide375

Detection of Advanced Oxidation Protein Products in Patients with Chronic Kidney Disease by A Novel Monoclonal Antibody386

Vascular Insulin Resistance Related to Endoplasmic Reticulum Stress in Aortas from a Rat Model of Chronic Kidney Disease396

Advanced Oxidation Protein Products Inhibit Differentiation and Activate Inflammation in 3T3-Ll Preadipocytes411

Advanced Oxidation Protein Products Induce Inflammatory Response and Insulin Resistance in Cultured Adipocytes Via Induction of Endoplasmic Reticulum Stress422

Asymmetrical Dimethylarginine Triggers Lipolysis and Inflammatory Response Via Induction of Endoplasmic Reticulum Stress in Cultured Adipocytes435

Advanced Oxidation Protein Products Induce Mesangial Cell Perturbation Through PKC-Dependent Activation of NADPH Oxidase447

Ethanol Extraction of Picrorhiza Scrophulariiflora Prevents Renal Injury in Experimental Diabetes Via Anti-Inflammation Action460

Advanced Oxidation Protein Products Promote Inflammation in Diabetic Kidney through Activation of Renal Nicotinamide Adenine Dinucleotide Phosphate Oxidase470

1,25-Dihydroxyvitamin D Improved the Free Fatty-Acid-Induced Insulin Resistance in Cultured C2C12 Cells483

Phenotypic and Functional Characteristics of Macrophage-Like Cells Differentiated in Pro-Inflammatory Cytokine-Containing Cultures490

三、侯凡凡院士学术年表500

侯凡凡院士在SCI收录期刊发表的社论和特邀述评500

侯凡凡院士在SCI收录期刊发表的共同作者论著501

侯凡凡院士承担的主要科研项目目录503

侯凡凡院士主要国际会议演讲目录504

第三部分 治学之道507

努力作科学而不是努力作文章509

凡凡女人心,不凡医者仁心路511

漫漫行医路 浓浓鱼水情514

循证医学可显著提高医疗卫生活动效率519

第四部分 大师风范521

医者仁心 师者爱心 学者恒心——记侯凡凡院士523

第五部分 社会影响527

不凡医者仁心路529

最是那昂首的妩媚530

走近女院士——侯凡凡535

与病人交心才能确保治疗效果537

我不认为我是大器晚成539

既然当了医生,就得当位好医生542

南方医院侯凡凡院士入选“全国医患和谐典型人物”544

当医生就要把心交给患者545

南方医院《关于开展向侯凡凡同志学习的决定》548

病房没有关门,我就不能走远550

技高为师 身正为范552

第六部分 人生风采555

成长经历557

医疗科研559

国际交流564

历史时刻567

幸福生活569

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